منابع مشابه
Evaluation of in-vitro antimicrobial activity of some newly synthesized 7-hydroxy 4-methyl coumarin congeners
A series of substituted 8-arylazo 7-hydroxy 4-methyl coumarin (4a-4g) were synthesized and in-vitro evaluation for their preliminary antibacterial activities against E.coli, Staphylococcus aurous, Bacillus subtilis and Pseudomonas aeroginosa were carried out by agar-well diffusion method. Initially, the diazotized primary aryl amines, 3a-3g were synthesized and followed by coupling with 7-hydro...
متن کاملEfficacy of 4-methyl-7-hydroxy coumarin derivatives against vectors Aedes aegypti and Culex quinquefasciatus.
4-Methyl-7-hydroxy coumarin is considered as a lead molecule as a biopesticide. Its mono bromo and tribromo derivatives were synthesized. Two more derivatives were synthesized by acylation. Compound 1 (3,6,8-tribromo-7-hydroxy-4-methyl-chromen-2-one) was found to be the most potent against IVth instar larvae of C. quinquefasciatus and A. aegypti the LC50 being 1.49 and 2.23 ppm respectively. It...
متن کاملComparative Study of the Synthesis of 7 Hydroxy-4-Methyl Coumarin Mannich Bases by Conventional and Microwave Method
Present work describes the synthesis of coumarin Mannich bases 4-7 by the application of Mannich reaction on 7-hydroxy-4-methyl coumarin 3 using conventional as well as microwave technology to compare the feasibility, reaction time and yield of the product. For this, 7-hydroxy-4-methyl coumarin 3 was prepared using Pechmann condensation reaction and Mannich bases (4-7) were synthesized by the r...
متن کاملTriphenylphosphine mediated synthesis of functionalized aryl-vinyl ethers from7-hydroxy coumarin and methyl acetylene carboxylate
7-hydroxy coumarin undergoes neutral conditions with alkyl propiolates in the presence of triphenylphosphine, and bysubstituation the corresponding aryl vinyl ethers was obtained in good yields
متن کاملSynthesis and characterization of some new 4-hydroxy-coumarin derivatives.
Some novel coumarins were synthesized starting from 4-hydroxycoumarin and methyl bromoacetate. The structures of the newly obtained compounds were confirmed by elemental analysis, mass, IR and NMR spectra.
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ژورنال
عنوان ژورنال: International Journal of Current Microbiology and Applied Sciences
سال: 2019
ISSN: 2319-7692,2319-7706
DOI: 10.20546/ijcmas.2019.804.318